Becoming fat – adipogenesis and beyond

Date Wednesday, October 07, 2009, 10:30 - 16:30
Location BMB Seminar room, University of Southern Denmark, Campusvej 55, Odense
Organizers The Danish Biochemical Society and the Danish PhD-School of Molecular Metabolism

Meeting abstract

Adipogenesis is the process by which fibroblastic preadipocyte precursors are converted into fat laden adipocytes. This process is regulated by external signals impacting on the preadipocytes as well as by an intricate network of signals and transcriptional regulators in the cells. Adipose tissue plays a central role in maintaining whole body lipid and glucose homeostasis, and recent advances in the field indicate that both white and brown adipocytes are of importance also in adult humans. White adipocytes store excess lipid and thereby protect other tissues from toxic accumulation of lipids, and they secrete hormones affecting whole body insulin sensitivity. Brown adipocytes oxidize fatty acids to dissipate stored energy as heat in response to cold and overnutrition. This symposium focuses on molecular pathways regulating adipogenesis and on the metabolic impact of adipogenesis on whole body physiology.

Preliminary Program

10.00 – 10.30


10.30 – 10.40

Anne Bugge, University of Southern Denmark: Introduction.

10.40 – 11.40

Mitch Lazar, Institute of Diabetes, Obesity, and Metabolism, University of Pennsylvania, Philadelphia, USA: PPARγ and epigenetic regulation of adipogenesis

11.40 – 12.10

Dominique Langin, Institut de Médecine Moléculaire de Rangueil, Université Paul Sabatier, Toulouse, France: Metabolism and inflammation in human adipose tissue

12.10 – 13.30

Lunch break and exhibition

13.30 – 14.00

Susanne Mandrup, Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense, Denmark: PPARγ as inducer of lipogenic gene programs

14.00 – 14.30

Soazig Le Lay, Centre de recherche Biomédicales des Cordeliers, Paris, France: Caveolin proteins and adipocyte lipid droplet storage

14.30 – 15.00

Eric Kalkhoven, Metabolic and Endocrine Diseases, UMC Utrecht, Utrecht, The Netherlands: Generalized and partial lipodystrophies

15.00 – 15.30

Coffee and exhibition

15.30 – 16.00

Jan Nedergaard, The Wenner-Gren Institute, Stockholm University, Stockholm, Sweden: Brown adipose tissue in mice and men

16.00 – 16.30

Jacob Bo Hansen, Department of Biomedical Sciences, University of Copenhagen, Blegdamsvej 3, 2200 Copenhagen, Denmark: Molecular studies of the postnatal transformation of brown to white adipose tissue in large mammals

The symposium is gratefully sponsored by Novo Nordisk and the Danish PhD-School of Molecular Metabolism, University of Southern Denmark.

Novo nordisk logo PhD-skolen i molekylær metabolisme


Everybody is welcome. Registration is required. 

Secretariat and vendor contact

Vivian Juhl, Danish Biochemical Society, Dept. of Clinical Biochemistry, Glostrup Hospital, 2600 Glostrup, Denmark. Tel: