Gene Targeting in Mice

Date	Thursday, July 10, 2008, 13:00 - 17:00
Location	The Lundbeck Auditorium, Copenhagen Biocenter, Ole Maaløes vej 5, Copenhagen, Denmark
Organizers	Tuula Kallunki, Danish Cancer Society and Steen Gammeltoft, Glostrup Hospital

Program

13.00 – 13.05	Tuula Kallunki, Danish Cancer Society: Welcome.
Session 1:	Homologous recombination in embryonal stem cells
13.05 – 13.50	Nobel lecture: Oliver Smithies, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA: Gene targeting approaches to complex genetic diseases.
13.50 – 14.30	Josef M. Penninger, Institute of Molecular Biotechnology of the Austrian Academy of Science, Vienna, Austria: From a little knock-out mouse to global understanding of bone metabolism.
14.30 – 15.00	Nadia Rosenthal, Mouse Biology Unit, EMBL Monterotondo Outstation, Monterotondo, Rome, Italy: The mouse ascending: perspectives for human-disease models.
15.00 – 15.30	Refreshments
Session 2:	Knockout mice in biomedical research
15.30 - 16.00	Marc Caron, Department of Cell Biology, Duke University Medical Center, Durham, NC, USA: Genetic Animal Models of CNS Disorders: Implications for therapies.
16.00 – 16.30	Henrik Semb, Stem Cell Center, Lund University, Lund, Sweden: Gene targeting in human embryonic stem cells: properties and applications.
16.30 – 17.00	Lars Bo Nielsen, Department of Clinical Biochemistry, Rigshospitalet, Copenhagen, Denmark: Mouse models to study a new apolipoprotein (apoM) affecting lipoprotein metabolism and atherosclerosis.
17.00 – 17.30	Cord Brakebusch, Biotech Research and Innovation Centre, Copenhagen Biocenter, Ole Maaløes Vej 5, Copenhagen, Denmark: Function of Rho GTPases in skin.